Fluoxetine for Dogs Sep 6, 2009
Fluoxetine is a fairly long-acting medication, with an elimination half-life of 2-3 days for fluoxetine and 7-9 days for norfluoxetine (an active metabolite of fluoxetine) ... Fluoxetine may increase the half-life of drugs such as diazepam and alprazolam, making them more effective for an extended period of time. (Suite101.com)
More Cowbell... er, Obama Sep 4, 2009
The networks are chagrined about this, not least because the ratings half-life of these events is severe. (Fox's broadcast network beat out the other networks by running "So You Think You Can Dance" instead of his last prime-time press conference. (Townhall.com)
Pet Talk: Every hurricane report stirs up images of animals lost Sep 2, 2009
Some of them, before they landed at the shelter, had been on their own in the post-disaster turmoil for weeks, scrounging a mean, half-life existence, finally so weak that animal control could approach them; some had been cared for by their owners, but couldn't be kept contained because the house was in tatters and fences had blown away; some arriving with litters because so few Southerners sterilize pets; many of them the very last possession finally given up by people decimated, broke and... (USA Today -- Life)
Survival trumps aesthetics Aug 30, 2009
Nuclear power: The waste is the most toxic stuff in the cosmos and has a half life of 28,000 years. The fuel can be diverted toward civilization-busting bomb production. (Logan Herald Journal, UT)
Bookman says it well on odious black agenda memo Aug 29, 2009
2) Glenn Beck has a short half life left at even a fake news station like Faux. While he s there to stoke their racist base, about 40 sponsers have dropped him. (Atlanta Journal-Constitution -- Opinion)
How deadly are cosmic rays? Aug 28, 2009
It is also radioactively unstable, with a half-life of 1. 5 million years, so it must have come from a fairly recent supernova. (MSNBC -- Technology)
State approves methadone clinic Aug 28, 2009
goatwoman wrote on Aug 28, 2009 12:56 AM:" WTH what facts do you have? Once again Suboxone or Subutox are better meds for rx drug addiction, NOT methadone. Check out the death rates from this med with an incredible half life and interactions. Plus, do you condone giving methadone to pregnant women?? Give me a break. You must be an employee. I pray you will accept accountability for this clinic at this site and the damage it will cause. I have facts, and you have delusions. ". Member ID. (Columbia Daily Herald, TN)
Shire in partnership with Santaris Pharma Aug 25, 2009
The LNAs are designed to improve the drug-like qualities of resulting therapeutics, called oligonucleotides, by boosting resistance to metabolism, increasing half-life and improving tissue uptake. Shire (NASDAQ:SHPGY) aims to strengthen its human genetic therapies business based in Cambridge, Mass. (Philadelphia Business Journal, PA)
Studies challenge vertebroplasty, yet patients and doctors say it works Aug 24, 2009
The Mayo Clinic study noted that the half-life of the local anesthetic used in the surgery (sham and real) is only 3 hours, meaning it is unlikely that the drug would have long-lasting pain-relief effects. They are tracking the outcomes. (Boston Globe)
Imogen Heap, 'Ellipse' Aug 24, 2009
Even when Heap abandons the Pro Tools, as on the delicate piano ballad Half Life, she displays an impeccable ear for gorgeous melodies and elegant arrangements. Ellipses usually signify that there s more to come; Ellipse simply confirms that Heap has arrived. (Boston Globe)
Novel polymer could improve protein-based drugs Aug 20, 2009
"The conventional compound myoglobin had a half-life of three minutes and was totally eliminated by two hours," Chilkoti explained. "By contrast, the new compound had a half-life 40 times greater and remained in circulation for 18 hours. The longer a protein remains in the system and is active, the more it helps the patient.". (EurekAlert!)
The "Zimdollar:" Dead, But Still Used For Bus Fare Aug 16, 2009
Half-life Of The Zimbabwe Dollar: Dead, But Still Used For Political Debates And For Bus Fare. Font size. (CBS News -- World)
Hope's gone AWOL in Echo platoon Aug 11, 2009
Some of them, however, are offered a free pass out of this military half-life - but only if they agree to deploy to Afghanistan or Iraq. Specialist Kevin McCormick, 21, who was held in Echo Platoon. (Asia Times Online)
Valve Studying Sign Language Aug 11, 2009
They entirely self-funded their first project, Half-Life, which wound up turning PC first-person shooters on their head when it was released two years later. Born: November 3, 1962. (IGN PC Games)
Argosy Energy Inc. Announces 2009 Second Quarter Results Aug 7, 2009
Statements relating to "reserves" or "resources' are deemed to be forward looking statements, as they involve the implied assessment, based on certain estimates and assumptions, that the reserves and resources described can be profitably produced in the future.Investors should not place undue reliance on forward-looking statements as there can be no assurance that the plans, intentions or expectations upon which they are based will occur. These forward-looking statements are made as of the date... (CCNMatthews Press Releases)
Dioxin Decomposition In The Yushchenko Case: Elimination Rate Faster Than Expected Aug 6, 2009
They also uncovered a massive reduction in the elimination half-life, down to about 16 months instead of the previously observed five to ten years. The elevated dosage had obviously caused the body to increase its production of the enzyme responsible for the decomposition of dioxin. (Science Daily)
Scientists checking Nevada Test Site groundwater Aug 1, 2009
It has a half-life of more than 12 years, meaning that's the time it takes for half of its radioactive atoms to decay. Other isotopes with much longer half-lives such as those from chlorine, iodine and technetium have dissolved and are moving along with the water. (San Francisco Chronicle -- Science)
SDK Develops Organic EL Devices with Light Output of 40% Jul 28, 2009
SDK has already achieved a luminance half life of approximately 10,000 hours for white lighting through improvements in the phosphorescent-polymer materials ... The three parties will also work to improve coating property of the phosphorescent polymer and prolong the device life, aiming to achieve a 150 lm/W emissive efficiency and a luminance half life of approximately 50,000 hours for white lighting by 2015. (JCN Network, Japan)
Gov't considers 7 states for mercury site Jul 24, 2009
"I don't like it," waitress Amanda Wyrick said as she poured a Half-Life Hefeweizen for a customer at Atomic Ale Brewpub and Eatery. "I would rather it not be close to me.". (Anchorage Daily News)
Atomic attraction Jul 23, 2009
Along the main street is the Atomic brew pub, where beers are given names like Atomic Amber and Half-life Hefeweisen. It is a gimmick, yet locals and tourists are drawn to its odd charm. (BBC News -- Americas)
Tobira Therapeutics Inc. Announces Phase I Data Demonstrating Pharmacokinetic Properties of TAK-652 for the Treatment of HIV Jul 22, 2009
- Long serum half-life allows for once-daily dosing. PRINCETON, N.J. and SAN DIEGO, July 22 /PRNewswire/ -- Tobira Therapeutics Inc., a clinical stage biotechnology company committed to research and product discovery for the treatment of life-threatening and life-altering infectious diseases, today announced pharmacokinetic data and results from two Phase I pharmacokinetic studies for TAK-652, an investigational compound being developed for the treatment of HIV. These data suggest that TAK-652... (PR Newswire)
Bringing together generations Jul 17, 2009
The small version created such good will that Kaib was asked to create a half-life sized version, which was completed by Christmas, 1945. The figures are constructed of concrete on a wire frame with plaster hand carved and painted for the detail work. (Mid Iowa Enterprise, IA)
Pesticide Linked to Parkinson's Disease Jul 15, 2009
Also, the half-life of the pesticide is seven to eight years, so it stays in the body for a long time. . (Newsmax)
XOMA Announces Positive Results From U.S. Phase 1 Trial of XOMA 052 in Type 2 Diabetes Jul 15, 2009
The pharmacokinetic results demonstrate a 23 day half-life in the systemic circulation, typical for monoclonal antibodies and consistent with monthly or less frequent dosing ... XOMA 052 has a half-life of 22 days ... Based on its binding properties, specificity to IL-1 beta and half-life, XOMA 052 may provide convenient dosing of once per month or less frequently. (Primezone Releases)
Pesticide Levels In Blood Linked To Parkinson's Disease Jul 15, 2009
Also, the half-life of the pesticide is seven to eight years, so it stays in the body for a long time. Parkinson s disease is more common among rural men than other demographic groups, but it is not a matter of a single factor causing the devastating disease, Dr. German said. (Science Daily)
Plastics Chemical, Bisphenol A, Retards Growth, Function Of Adult Reproductive Cells Jul 10, 2009
BPA has a short half-life, Peretz said, and the chemical is quickly eliminated from the body. The fact that so many people tested positive "probably means that we're being constantly exposed to BPA," she said. (Science Daily)
Is obesity an oral bacterial disease? Jul 9, 2009
Is obesity an oral bacterial disease. Public release date: 8-Jul-2009. (EurekAlert!)
Raxibacumab for the Treatment of Inhalational Anthrax Jul 9, 2009
In human subjects, intravenous raxibacumab at a dose of 40 mg per kilogram had a half-life of 20 to 22 days and provided a maximum concentration of the drug in excess of levels that are protective in animals. Concentrations of raxibacumab provide a surrogate end point that should be predictive of clinical benefit. (New England Journal of Medicine)
Remote-control closed system invented for inserting radio-active atoms inside fullerenes Jul 8, 2009
It all takes less than a day, which is important because 177Lu has a half life of six and one-half days. "So we can't take 30 days to make the product," said Duchamp. (EurekAlert!)
Cocaine-Laden Plane Plunges in Ocean Jul 2, 2009
What is the biological half life of cocaine. Does frozen fish stay the effects of the cocaine or reduce them. (CBS News)
Monday's TV: Flight Of The Conchords Jun 23, 2009
Strontium-90 has a half-life and so do motoring shows. This one has ceased to glow in the dark. (Sydney Morning Herald -- Entertainment)
GEORGE B. KAUFFMAN: Chemical elements, then and now Jun 21, 2009
He discovered Technetium-99m, an element unknown to the textbook of my adolescence but now the most widely used diagnostic radioisotope whose short half-life reduces the patient's radiation exposure. While a guest on the "Quiz Kids" radio program on Nov. 11, 1945, Seaborg announced his discovery of Americium and Curium in response to a youngster's asking whether he had discovered any new elements. (Fresno Bee -- Opinion)
Land of the lost global warming skeptics Jun 20, 2009
"has also garnered praised for her award winning performance as Alyx Vance in the "Half Life 2" games series.". I informed my son of this and his eyes widened. (Salon)
Antidepressants May Reduce Male Fertility Jun 17, 2009
The drug was used because of its relatively short half-life and because it has previously shown to exert the strongest effect in delaying ejaculation. DNA fragmentation, defined as missing pieces of genetic code in the sperm DNA, was measured using an assay called terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL). (Newsmax)
Versartis publishes 2 preclinical abstracts at American Diabetes Association meeting Jun 6, 2009
New company focusing on extending half life of drugs for metabolic and endocrine diseases ... Versartis, through a unique licensing agreement with Amunix, Inc., uses the proprietary Amunix recombinant PEGylation (rPEG) technology to extend the half life of established biologics. (EurekAlert! -- Business News)
Zap! Wrinkles And Sun Spots Be Gone Jun 2, 2009
Collagen, the molecule that this procedure is really trying to get the body to produce, has a half life of about 15 years. We would expect that, to the extent that patients improvement is based on collagen production, their results would last a very long time, he says. (Science Daily)
OncoGenex Pharmaceuticals Announces OGX-427 Treatment Demonstrates Safety, Evidence of Declines in Circulating Tumor Cells and Reductions in Tumor Markers in a Phase 1 Cancer Trial May 31, 2009
- The half-life of OGX-427 in the blood remained constant, although there appeared to be an increase in maximum blood levels and a corresponding decease in blood clearance of OGX-427 as doses were escalated. The combination of 800 mg OGX-427 with docetaxel was also well tolerated and escalation to 1000 mg OGX-427 with docetaxel will be evaluated next. (PR Newswire)
Gene Therapy Could Expand Stem Cells' Promise May 23, 2009
"Almost all therapeutics we use have a half life. They only last a certain amount of time," Dr. Crystal says. "Stem cells are the opposite. Once the future stem cell therapist does the therapy, stem cells have the innate potential to produce more cells.". (Science Daily)
Rational Design Of Vaccines: A Long But Essential Journey May 17, 2009
ScienceDaily (May 16, 2009) The holy grail of the defence mechanism against infectious diseases and tumours has not yet been discovered. In the search for a master switch in the immune apparatus of humans and animals, many strategies still need to be explored before the enormous potency of this complex system can be activated and controlled in the right manner. (Science Daily)
American Chemical Society's weekly PressPac -- May 6, 2009 May 11, 2009
Cobalt, present in some alloys used in the reactors' water systems, is a major contributor toward this problem because of its long half-life. In the study, the researchers created an adsorbent material that unlike conventional ion-exchange resins that are frequently used in reactors is selective for cobalt but has the unique ability of disregarding iron-based ions. (EurekAlert!)
Skin color clue to nicotine dependence May 9, 2009
King and colleagues surmise that nicotine's half-life may, along with tobacco toxicants, be extended due to the accumulation in melanin-containing tissues. Statistical analyses of data on the three measures of smoking -- cigarettes per day, FTND score, and cotinine levels -- along with a host of other variables including age, education and social demographics of the smokers, reveal that facultative melanin -- the total amount of melanin acquired genetically plus the amount from the tanning... (EurekAlert!)
Hey pig, yeah you May 5, 2009
There s nursery rhymes, where pigs can count; Animals, where they pronounce charade in an un-American fashion; Babe, where they can talk; Animal Farm, where they can rule the world; Brazil and Half-Life 2, where oppressive people wear pig masks; and Spirited Away, where people literally become pigs. That s just recent art. (McKinney Courier-Gazette, TX)
Targeting Tumors Using Tiny Gold Particles May 5, 2009
Bhatia's team developed a polymer coating for the particles that allows them to survive in the bloodstream longer than any other gold nanoparticles (the half-life is greater than 17 hours). In designing the particles, the researchers took advantage of the fact that blood vessels located near tumors have tiny pores just large enough for the nanorods to enter. (Science Daily)
Agency aims to reduce tritium May 1, 2009
Tritium has a half-life of 12. 5 years and must be replenished periodically. (The Augusta Chronicle)
No 'Burp' Accelerating Climate Change? Wetlands Likely Source Of Methane From Ancient Warming Event Apr 28, 2009
Levels of carbon-14, which has a half-life of 5,730 years, were too high in the methane to have come from clathrates, the researchers concluded. "This study is important because it confirms that wetlands and moisture availability change dramatically along with abrupt climate change," said Severinghaus. (Science Daily)
City skyline or marketing device? Apr 28, 2009
Page last updated at 11:10 GMT, Monday, 27 April 2009 12:10 UK. Changing Cityscapes: Manchester. (BBC News -- UK)
Mersana's Second Development Candidate, XMT-1107, Shows Superior Pharmacokinetics and Anti-Tumor Activity in Studies Presented at American Association of Cancer Research Meeting Apr 20, 2009
The data suggest that the slow rate of release of XMT-1191 from the polymer conjugate XMT-1107 provided a low but consistent exposure to the highly active XMT-1191 small molecule, providing an apparent half life of 22 hours compared with a half life of less than five minutes with free XMT-1191 administration. The data are consistent with the significantly higher in vivo activity seen for XMT-1107 relative to XMT-1191 in xenograft activity reported in a separate poster. (PR Newswire)
Prescription drugs top Oregon overdose stats Apr 1, 2009
Methadone is considered cheap and long-lasting, with what Gunson described as a 56-hour half-life. That means it may take several days to have an effect. (OregonLive, OR -- News)
Mistakes begetgreater mistakes Mar 24, 2009
0 trillion was judged to have had too short of a half-life. So the Fed is now to balloon its liabilities to $3. (Asia Times Online)
Ga. agriculture department offers seed help Mar 20, 2009
Most modern pesticides have a relatively short half-life (the time it takes for them to break down). If you have concerns about edible plants being affected, soap and water will usually remove pesticide residue. (Atlanta Journal-Constitution -- Home & Garden)
Ongoing worldwide shortage of medical isotopes could threaten patient care, says expert Mar 19, 2009
Around 80 per cent of clinical nuclear medicine work is dependent on the routine availability of the radioisotope molybdenum-99 (Mo-99), from which Tc-99m is derived, which has a half-life of three days and cannot therefore be stockpiled. Ninety-five per cent of the world's Mo-99 is produced by five commercial nuclear reactors NRU at Chalk River in Canada, HFR at Petten in The Netherland, BR-2 at Fleurus in Belgium, OSIRIS at Saclay in France and SAFARI-1 at Pelindaba in South Africa. (EurekAlert! -- Business News)
Frankenstein Conquers the World Mov... Mar 12, 2009
They're not very convincing, but for those nurturing a Keystone beer or MD 20/20 recreational high, the climactic, half-life wrestling match featuring Kid Frankenstein versus Baragon the Terrible will surely entertain. Frankenstein Conquers the World hit Japanese movie theaters on August 8. (Suite101.com)
Fest's Full Slate Mar 10, 2009
Other highlights include films by Deepa Mehta ("Heaven on Earth") and her brother, noted still photographer Dilip Mehta (a documentary, "The Forgotten Woman"); Ang Lee in person to discuss a screening of his 2007 film "Lust, Caution"; a 1962 Charlton Heston movie, "Diamond Head," that looks at race relations in Hawaii upon its impending statehood; a retrospective of 81-year-old Japanese media artist Takahiko Iimura; and new films by China's Jia Zhangke ("24 City") and Bay Area filmmakers... (San Francisco Chronicle -- Entertainment)
Chu: Yucca no longer option for nuclear waste Mar 8, 2009
Cognitus wrote on Mar 7, 2009 1:33 PM:" Yucca Mountain was controversial from the beginning as it appears to be located in an earthquake zone with a fault running through the area. They should have started looking for a better location many years ago. Remember this stuff has a half-life of thousands of years, so it needs to be VERY ISOLATED in a place notlikely to be disturbed by man or geological forces. ". Most commented. (Mattoon Journal-Gazette, IL)
Nuclear relic found in bottle Mar 3, 2009
It has a half-life (the time it takes for half the radioactive nuclei in a sample to decay) of 24,110 years. The bottle in question was discovered in a burial trench at the Hanford nuclear site in Washington state, north-western US.. (BBC News -- Americas)
No surprise: 'I' is our oldest word Feb 28, 2009
A word such as throw is described as having a half-life of more than 900 years, but, since there are 42 unrelated words for it across the various Indo-European languages, it is likely to eventually be replaced in 10 of those languages by the year 3,000. Words such as squeeze, guts and stick are also headed for the scrap heap, Prof. (Globe and Mail)
Legislature approves nuke bill Feb 27, 2009
What is the half-life of the nuclear fuel. And what have you been smoking. (Atlanta Journal-Constitution -- Metro)
New models question old assumptions about how many molecules it takes to control cell division Feb 25, 2009
To achieve this level of control, the Virginia Tech researchers conclude, in their PNAS paper, that 1) the average number of specific mRNA molecules must be 5 to 10 times larger than the generally accepted value, or 2) the half-life of mRNA molecules must be 10 to 20 times shorter than the reported value, or 3) the cell must have specific mechanisms for noise reduction in its mRNA populations. Or some combination of these strategies. (EurekAlert!)
The comforting presence of absent friends Feb 23, 2009
But for now I prefer this half life where those we have lost occasionally appear on our computer screens to keep us company. Copyright. (Jakarta Post, Indonesia -- Features)
Nuclear power right for Utah Feb 17, 2009
Articles receiving the most comments in the past 72 hours. Do you use coupons at the grocery store. (Logan Herald Journal, UT)
Dynamic distribution and expression in vivo of human interferon gamma gene delivered by adenoviral vector Feb 16, 2009
Considering about the fact that the clinical application of recombinant IFNgamma was limited by its short half-life and systemic side effects, we developed a recombinant adenoviruses Ad-IFNgamma. Methods. (BioMed Central)
Radioimmunotherapy: Promising treatment for HIV infection and viral cancers Feb 15, 2009
Bismuth-213 was chosen because of several characteristics, including a half-life, or decay rate, of 46 minutes. Such a short half-life rate allows just enough time for the treatment to be administered and for the radioactive antibodies to do their job. (EurekAlert!)
Nuclear power in the Nordic countries: Recalled to half-life Feb 14, 2009
Recalled to half-life. Feb 12th 2009 | HELSINKIFrom The Economist print edition. (The Economist)
First person shooter games found to be helpful in fire safety training Feb 7, 2009
As per the research, commercial games like Doom 3 and Half Life 2 can be utilized in building up such virtual worlds where people learn the procedures of escaping fire with the help of the underlying software codes. As a part of the research, a 3D model of the real world and three fire evacuation scenarios complete with smoke and fire were developed with the help of these games. (TechShout!)
New guideline for prescribing opioid pain drugs published Feb 7, 2009
Because of its long half-life and variable pharmacokinetics, the panel recommends methadone not be used to treat breakthrough pain or as an as-needed medication. Abusers: Chronic opioid therapy must be discontinued in patients known to be diverting their medication or in those engaging in serious aberrant behaviors. (EurekAlert!)
